BDBM50070880 CHEMBL48315::Sodium; (Z)-2-benzo[1,2,5]thiadiazol-5-yl-4-(4-isopropoxy-phenyl)-4-oxo-3-(3,4,5-trimethoxy-benzyl)-but-2-enoate

SMILES COc1cc(C\C(C(=O)c2ccc(OC(C)C)cc2)=C(\C([O-])=O)c2ccc3nsnc3c2)cc(OC)c1OC

InChI Key InChIKey=MDILXATXKKYABM-UHFFFAOYSA-M

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50070880   

TargetEndothelin-1 receptor(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM50070880(Sodium; (Z)-2-benzo[1,2,5]thiadiazol-5-yl-4-(4-iso...)
Affinity DataIC50: 64nMAssay Description:In vitro ability to inhibit specific [125I]ET1 binding to rat aorta membranes Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMed
TargetEndothelin receptor type B(Pig)
Merck

Curated by ChEMBL
LigandPNGBDBM50070880(Sodium; (Z)-2-benzo[1,2,5]thiadiazol-5-yl-4-(4-iso...)
Affinity DataIC50: 550nMAssay Description:In vitro ability to inhibit specific [125I]ET1 binding to porcine kidney (inner medulla) membranes Endothelin B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMed