BDBM50070889 CHEMBL51030::Sodium; (Z)-2-benzo[1,2,5]thiadiazol-5-yl-4-(4-methoxy-phenyl)-3-(4-methylsulfanyl-benzyl)-4-oxo-but-2-enoate

SMILES COc1ccc(cc1)C(=O)C(\Cc1ccc(SC)cc1)=C(/C([O-])=O)c1ccc2nsnc2c1

InChI Key InChIKey=GWLKGKWFFNSBNX-UHFFFAOYSA-M

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50070889   

TargetEndothelin-1 receptor(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM50070889(Sodium; (Z)-2-benzo[1,2,5]thiadiazol-5-yl-4-(4-met...)
Affinity DataIC50: 17nMAssay Description:In vitro ability to inhibit specific [125I]ET1 binding to rat aorta membranes Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMed
TargetEndothelin receptor type B(Pig)
Merck

Curated by ChEMBL
LigandPNGBDBM50070889(Sodium; (Z)-2-benzo[1,2,5]thiadiazol-5-yl-4-(4-met...)
Affinity DataIC50: 3.20E+3nMAssay Description:In vitro ability to inhibit specific [125I]ET1 binding to porcine kidney (inner medulla) membranes Endothelin B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMed