BDBM50070891 CHEMBL48458::Sodium; (Z)-2-benzo[1,2,5]thiadiazol-5-yl-4-(4-fluoro-2-methoxy-phenyl)-4-oxo-3-(3,4,5-trimethoxy-benzyl)-but-2-enoate

SMILES COc1cc(C\C(C(=O)c2ccc(F)cc2OC)=C(\C([O-])=O)c2ccc3nsnc3c2)cc(OC)c1OC

InChI Key InChIKey=XYGIELPLBVNTKG-UHFFFAOYSA-M

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50070891   

TargetEndothelin-1 receptor(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM50070891(Sodium; (Z)-2-benzo[1,2,5]thiadiazol-5-yl-4-(4-flu...)
Affinity DataIC50: 12nMAssay Description:In vitro ability to inhibit specific [125I]ET1 binding to rat aorta membranes Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMed