BDBM50070975 3-{1-benzyloxymethyl-2-[1-methylsulfonylspiro[2,3-dihydro-1H-indole-3,4'-(hexahydropyridine)]-1-yl]-2-oxoethylaminomethyl}benzonitrile::CHEMBL54996

SMILES CS(=O)(=O)N1CC2(CCN(CC2)C(=O)C(COCc2ccccc2)NCc2cccc(c2)C#N)c2ccccc12

InChI Key InChIKey=CJKYRASQASCQQD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50070975   

TargetSubstance-P receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50070975(3-{1-benzyloxymethyl-2-[1-methylsulfonylspiro[2,3-...)
Affinity DataIC50: 152nMAssay Description:Ability to displace [125I]-substance P from hNK1 receptor in chinese hamster ovarian (CHO) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed