BDBM50071135 (E)-5-{4-[4-(4-Cyclohexyl-butylcarbamoyl)-oxazol-2-yl]-phenyl}-5-pyridin-3-yl-pent-4-enoic acid::CHEMBL418323

SMILES OC(=O)CC\C=C(/c1ccc(cc1)-c1nc(co1)C(=O)NCCCCC1CCCCC1)c1cccnc1

InChI Key InChIKey=SYUFSKPOVFADFD-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50071135   

TargetThromboxane-A synthase(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071135((E)-5-{4-[4-(4-Cyclohexyl-butylcarbamoyl)-oxazol-2...)
Affinity DataIC50: 3.17E+3nMAssay Description:In vitro inhibition of thromboxane synthase (TSI) activity was determined by using human serum levels of TXB2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071135((E)-5-{4-[4-(4-Cyclohexyl-butylcarbamoyl)-oxazol-2...)
Affinity DataKd:  93nMAssay Description:In vitro thromboxane receptor antagonism was determined using a human platelet binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed