BDBM50071136 (E)-7-{4-[(R)-4-(4-Cyclohexyl-butylcarbamoyl)-4,5-dihydro-oxazol-2-yl]-phenyl}-7-pyridin-3-yl-hept-6-enoic acid::CHEMBL56778

SMILES OC(=O)CCCC\C=C(/c1ccc(cc1)C1=N[C@H](CO1)C(=O)NCCCCC1CCCCC1)c1cccnc1

InChI Key InChIKey=LTCQRNQPODCPAS-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50071136   

TargetThromboxane-A synthase(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071136((E)-7-{4-[(R)-4-(4-Cyclohexyl-butylcarbamoyl)-4,5-...)
Affinity DataIC50: 82nMAssay Description:In vitro inhibition of thromboxane synthase (TSI) activity was determined by using human serum levels of TXB2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071136((E)-7-{4-[(R)-4-(4-Cyclohexyl-butylcarbamoyl)-4,5-...)
Affinity DataKd:  16nMAssay Description:In vitro thromboxane receptor antagonism was determined using a human platelet binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed