BDBM50071180 8-Methoxy-2-methyl-11,12-dihydro-3H,6aH,13H-6-oxa-3,12a-diaza-benzo[a]cyclopenta[h]anthracene-1-carboxylic acid ethyl ester::CHEMBL300987

SMILES CCOC(=O)c1c(C)[nH]c2ccc3OC4N(CCc5ccc(OC)cc45)Cc3c12

InChI Key InChIKey=JHBJXFJNSKBBLY-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50071180   

TargetMuscarinic acetylcholine receptor M2(Human)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50071180(8-Methoxy-2-methyl-11,12-dihydro-3H,6aH,13H-6-oxa-...)
Affinity DataIC50: 3.00E+3nMAssay Description:Evaluated for its binding affinity at human muscarinic receptor m2 by displacement of [3H]NMS binding using membranes from transfected chinese hamste...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M4(Human)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50071180(8-Methoxy-2-methyl-11,12-dihydro-3H,6aH,13H-6-oxa-...)
Affinity DataIC50: 6.03E+3nMAssay Description:Evaluated for its binding affinity at human muscarinic receptor m4 by the displacement of [3H]NMS binding using membranes from transfected chinese ha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50071180(8-Methoxy-2-methyl-11,12-dihydro-3H,6aH,13H-6-oxa-...)
Affinity DataIC50: 8.21E+3nMAssay Description:Evaluated for its binding affinity at human muscarinic receptor m5 by the displacement of [3H]NMS binding using membranes from transfected chinese ha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50071180(8-Methoxy-2-methyl-11,12-dihydro-3H,6aH,13H-6-oxa-...)
Affinity DataIC50: 9.02E+3nMAssay Description:Compound was evaluated for its binding affinity at human muscarinic receptor m1 by displacement of [3H]NMS radioligand using membranes from transfect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50071180(8-Methoxy-2-methyl-11,12-dihydro-3H,6aH,13H-6-oxa-...)
Affinity DataIC50: 1.08E+4nMAssay Description:Compound was evaluated for its binding affinity at human muscarinic receptor m3 by the displacement of [3H]NMS radioligand using membranes from trans...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMed