BDBM50071197 4-(4-Phenyl-butyl)-1H-imidazole::CHEMBL296450

SMILES C(CCc1ccccc1)Cc1cnc[nH]1

InChI Key InChIKey=BQTXNCXSCSNHGA-UHFFFAOYSA-N

Data  3 KI  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50071197   

TargetHistamine H3 receptor(Guinea pig)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50071197(4-(4-Phenyl-butyl)-1H-imidazole | CHEMBL296450)
Affinity DataKd:  25.1nMAssay Description:Displacement of [3H]Nalpha-methylhistamine from histamine H3 receptors in homogenates of rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM50071197(4-(4-Phenyl-butyl)-1H-imidazole | CHEMBL296450)
Affinity DataKi:  2.10nMAssay Description:Inhibition of [125I]iodoproxyfan binding to human histamine H3 receptor of CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM50071197(4-(4-Phenyl-butyl)-1H-imidazole | CHEMBL296450)
Affinity DataKi:  12nMAssay Description:Binding affinity to rat Histamine H3 receptor in CHO-K1 cells using [125I]iodoproxyfan as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM50071197(4-(4-Phenyl-butyl)-1H-imidazole | CHEMBL296450)
Affinity DataKi:  56nMAssay Description:In vitro Histamine H3 receptor antagonist activity in an assay with K+-evoked depolarization-induced release of [3H]histamine from synaptosomes of ra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed