BDBM50071664 5-Amino-2-[1-(3,5-dibromo-4-hydroxy-phenyl)-meth-(E)-ylidene]-indan-1,3-dione::CHEMBL84807

SMILES Nc1ccc2C(=O)\C(=C/c3cc(Br)c(O)c(Br)c3)C(=O)c2c1

InChI Key InChIKey=LGMNYNVJHOKTDI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50071664   

TargetTyrosine-protein kinase Lck(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50071664(5-Amino-2-[1-(3,5-dibromo-4-hydroxy-phenyl)-meth-(...)
Affinity DataIC50: 32nMAssay Description:Inhibition of p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50071664(5-Amino-2-[1-(3,5-dibromo-4-hydroxy-phenyl)-meth-(...)
Affinity DataIC50: 460nMAssay Description:Inhibition of Src tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha/beta/gamma(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50071664(5-Amino-2-[1-(3,5-dibromo-4-hydroxy-phenyl)-meth-(...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of Protein Kinase A (PKA)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed