BDBM50071667 5-Amino-2-[1-(3,5-dichloro-4-hydroxy-phenyl)-meth-(E)-ylidene]-indan-1,3-dione::CHEMBL84808

SMILES Nc1ccc2C(=O)\C(=C/c3cc(Cl)c(O)c(Cl)c3)C(=O)c2c1

InChI Key InChIKey=QBYUXBSIKVMXQE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50071667   

TargetTyrosine-protein kinase Lck(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50071667(5-Amino-2-[1-(3,5-dichloro-4-hydroxy-phenyl)-meth-...)
Affinity DataIC50: 102nMAssay Description:Inhibition of p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50071667(5-Amino-2-[1-(3,5-dichloro-4-hydroxy-phenyl)-meth-...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of Src tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha/beta/gamma(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50071667(5-Amino-2-[1-(3,5-dichloro-4-hydroxy-phenyl)-meth-...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of Protein Kinase A (PKA)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed