BDBM50071855 4-(4-Benzyl-piperazin-1-yl)-2-trifluoromethyl-1H-benzoimidazole::CHEMBL88289

SMILES FC(F)(F)c1nc2c(cccc2[nH]1)N1CCN(Cc2ccccc2)CC1

InChI Key InChIKey=PSWUORNVMIRUSW-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50071855   

TargetD(2) dopamine receptor(Rat)
Wyeth-Ayerst Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50071855(4-(4-Benzyl-piperazin-1-yl)-2-trifluoromethyl-1H-b...)
Affinity DataKi:  0.510nMAssay Description:Affinity for Dopamine receptor D2 in rat striatal membranes for high agonist state using [3H]quinpiroleMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Wyeth-Ayerst Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50071855(4-(4-Benzyl-piperazin-1-yl)-2-trifluoromethyl-1H-b...)
Affinity DataKi:  2.90nMAssay Description:Affinity towards human Dopamine receptor D4.4 expressed in CHO cells using [3H]spiperoneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Wyeth-Ayerst Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50071855(4-(4-Benzyl-piperazin-1-yl)-2-trifluoromethyl-1H-b...)
Affinity DataKi:  3.30nMAssay Description:Affinity of compound for the Dopamine receptor D2 in rat striatal membranes was determined for low agonist state in rat striatal membranes using [3H]...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Wyeth-Ayerst Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50071855(4-(4-Benzyl-piperazin-1-yl)-2-trifluoromethyl-1H-b...)
Affinity DataKi:  4.10nMAssay Description:Affinity towards human Dopamine receptor D2 expressed in CHO cells using [3H]spiperoneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Wyeth-Ayerst Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50071855(4-(4-Benzyl-piperazin-1-yl)-2-trifluoromethyl-1H-b...)
Affinity DataKi:  15nMAssay Description:Affinity towards human Dopamine receptor D3 expressed in CHO cells using [3H]spiperoneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed