BDBM50071858 4-(4-Benzyl-piperazin-1-yl)-5-chloro-1H-indole::CHEMBL311539

SMILES Clc1ccc2[nH]ccc2c1N1CCN(Cc2ccccc2)CC1

InChI Key InChIKey=IRFLVVGRMBDQSJ-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50071858   

TargetD(4) dopamine receptor(Human)
Wyeth-Ayerst Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50071858(4-(4-Benzyl-piperazin-1-yl)-5-chloro-1H-indole | C...)
Affinity DataKi:  1.70nMAssay Description:Affinity towards human Dopamine receptor D4.4 expressed in CHO cells using [3H]spiperoneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Wyeth-Ayerst Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50071858(4-(4-Benzyl-piperazin-1-yl)-5-chloro-1H-indole | C...)
Affinity DataKi:  9.10nMAssay Description:Affinity for Dopamine receptor D2 in rat striatal membranes for high agonist state using [3H]quinpiroleMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Wyeth-Ayerst Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50071858(4-(4-Benzyl-piperazin-1-yl)-5-chloro-1H-indole | C...)
Affinity DataKi:  42nMAssay Description:Affinity of compound for the D2 receptors in rat striatal membranes was determined for low antagonist state in rat striatal membranes using [3H]spipe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Wyeth-Ayerst Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50071858(4-(4-Benzyl-piperazin-1-yl)-5-chloro-1H-indole | C...)
Affinity DataKi:  81nMAssay Description:Affinity towards human Dopamine receptor D2 expressed in CHO cells using [3H]spiperoneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Wyeth-Ayerst Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50071858(4-(4-Benzyl-piperazin-1-yl)-5-chloro-1H-indole | C...)
Affinity DataKi:  95nMAssay Description:Affinity towards human Dopamine receptor D3 expressed in CHO cells using [3H]spiperoneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed