BDBM50071947 4-[3-(1-Benzyl-piperidin-4-yl)-2-oxo-[1,3]diazepan-1-yl]-benzamidine::CHEMBL93480

SMILES NC(=N)c1ccc(cc1)N1CCCCN(C2CCN(Cc3ccccc3)CC2)C1=O

InChI Key InChIKey=PBKFFWDROFXKDQ-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50071947   

TargetSerine protease 1(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50071947(4-[3-(1-Benzyl-piperidin-4-yl)-2-oxo-[1,3]diazepan...)
Affinity DataKi: >1.60E+3nMAssay Description:Compound was tested for inhibition of trypsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50071947(4-[3-(1-Benzyl-piperidin-4-yl)-2-oxo-[1,3]diazepan...)
Affinity DataKi:  7.50E+3nMAssay Description:Compound was tested for inhibition of blood coagulation protein factor XaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50071947(4-[3-(1-Benzyl-piperidin-4-yl)-2-oxo-[1,3]diazepan...)
Affinity DataKi: >2.10E+4nMAssay Description:Compound was tested for inhibition of thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed