BDBM50072021 2,2,4-Trimethyl-2,10-dihydro-1H-pyrido[2,3-b]carbazole::CHEMBL329339

SMILES CC1=CC(C)(C)Nc2cc3[nH]c4ccccc4c3cc12

InChI Key InChIKey=ZKBIYCLPMIOTJI-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50072021   

TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072021(2,2,4-Trimethyl-2,10-dihydro-1H-pyrido[2,3-b]carba...)
Affinity DataIC50: 59nMAssay Description:Antagonist activity against human progesterone receptor B (hPR-B) in co-transfected CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072021(2,2,4-Trimethyl-2,10-dihydro-1H-pyrido[2,3-b]carba...)
Affinity DataKi:  112nMAssay Description:Displacement of [3H]progesterone from Progesterone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072021(2,2,4-Trimethyl-2,10-dihydro-1H-pyrido[2,3-b]carba...)
Affinity DataKi:  113nMAssay Description:Binding affinity against human progesterone receptor-A (hPR-A)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed