BDBM50072165 2-[1-Amino-1-(2-amino-phenylsulfanyl)-meth-(Z)-ylidene]-3-[3H-benzothiazol-(2Z)-ylidene]-succinonitrile::CHEMBL95905

SMILES Nc1ccccc1SC(=N)C(C#N)C(C#N)c1nc2ccccc2s1

InChI Key InChIKey=HWOMLSHWUKFYHI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50072165   

TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072165(2-[1-Amino-1-(2-amino-phenylsulfanyl)-meth-(Z)-yli...)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of the dual specificity kinase MEK-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072165(2-[1-Amino-1-(2-amino-phenylsulfanyl)-meth-(Z)-yli...)
Affinity DataIC50: 1.87E+4nMAssay Description:Ability to antagonise AP-1 transcriptional activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed