BDBM50072189 (7aS,8R)-7a-Methyl-2-oxo-2,3,4,7,7a,8,9,10,10a,10b,11,12-dodecahydro-indeno[4,5-c]quinolizine-8-carboxylic acid tert-butylamide::CHEMBL99615

SMILES CC(C)(C)NC(=O)[C@@H]1CCC2C3CCC4=CC(=O)CCN4C3=CC[C@]12C

InChI Key InChIKey=RNZZVODXMPJOQO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50072189   

Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50072189((7aS,8R)-7a-Methyl-2-oxo-2,3,4,7,7a,8,9,10,10a,10b...)
Affinity DataIC50: 122nMAssay Description:Compound was evaluated for the inhibition of human Steroid 5-alpha-reductase type 2 receptor from human prostate homogenates.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50072189((7aS,8R)-7a-Methyl-2-oxo-2,3,4,7,7a,8,9,10,10a,10b...)
Affinity DataIC50: 127nMAssay Description:Compound was evaluated for the inhibition of human Steroid 5-alpha-reductase type 1 from recombinant CHO cells; No inhibition up to 10 uM concentrati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed