BDBM50072207 CHEMBL97213::[4-(3,5-Bis-cyclopropylmethoxy-phenyl)-6-methoxy-2-methyl-quinazolin-7-yloxy]-acetic acid ethyl ester

SMILES CCOC(=O)COc1cc2nc(C)nc(-c3cc(OCC4CC4)cc(OCC4CC4)c3)c2cc1OC

InChI Key InChIKey=RYADKLVXEBSPMG-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50072207   

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50072207([4-(3,5-Bis-cyclopropylmethoxy-phenyl)-6-methoxy-2...)
Affinity DataIC50: 700nMAssay Description:Evaluated for its ability to inhibit PDE3.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50072207([4-(3,5-Bis-cyclopropylmethoxy-phenyl)-6-methoxy-2...)
Affinity DataIC50: 1.00E+4nMAssay Description:Evaluated for its ability to inhibit PDE4A.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Rat)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50072207([4-(3,5-Bis-cyclopropylmethoxy-phenyl)-6-methoxy-2...)
Affinity DataIC50: 6.10E+4nMAssay Description:Evaluated for its ability to inhibit PDE4B.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50072207([4-(3,5-Bis-cyclopropylmethoxy-phenyl)-6-methoxy-2...)
Affinity DataIC50: 1.00E+5nMAssay Description:Evaluated for its ability to inhibit PDE4D.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed