BDBM50072470 CHEMBL110412::{(S)-4-Methyl-7-[methyl-(6-trifluoromethyl-1H-benzoimidazol-2-ylmethyl)-carbamoyl]-3-oxo-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-2-yl}-acetic acid

SMILES CN(Cc1nc2ccc(cc2[nH]1)C(F)(F)F)C(=O)c1ccc2N[C@@H](CC(O)=O)C(=O)N(C)Cc2c1

InChI Key InChIKey=QWMJWEFRSJDVCR-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50072470   

TargetIntegrin alpha-V/beta-3(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072470({(S)-4-Methyl-7-[methyl-(6-trifluoromethyl-1H-benz...)
Affinity DataKi:  8.5nMAssay Description:Binding affinity evaluated against vitronectin receptor (alphaV-beta3) receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072470({(S)-4-Methyl-7-[methyl-(6-trifluoromethyl-1H-benz...)
Affinity DataIC50: 1.00E+3nMAssay Description:Effect against adhesion of HEK 293 cells transfected with human alpha-v beta-3 to vitronectin coated platesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed