BDBM50072781 (E)-7-{4-[4-(2-Cyclohexylmethoxy-ethylcarbamoyl)-oxazol-2-yl]-phenyl}-7-pyridin-3-yl-hept-6-enoic acid::CHEMBL346644

SMILES OC(=O)CCCC\C=C(/c1ccc(cc1)-c1nc(co1)C(=O)NCCOCC1CCCCC1)c1cccnc1

InChI Key InChIKey=WMXZEBHSAJEWND-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50072781   

TargetThromboxane-A synthase(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50072781((E)-7-{4-[4-(2-Cyclohexylmethoxy-ethylcarbamoyl)-o...)
Affinity DataIC50: 36.7nMAssay Description:In vitro for inhibitory activity against thromboxane synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50072781((E)-7-{4-[4-(2-Cyclohexylmethoxy-ethylcarbamoyl)-o...)
Affinity DataKd:  43.3nMAssay Description:In vitro for antagonistic activity against thromboxane synthase receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed