BDBM50072822 7-{3-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-propoxy}-3-hydroxymethyl-chromen-4-one::CHEMBL151475
SMILES OCc1coc2cc(OCCCN3CCC(CC3)c3noc4cc(F)ccc34)ccc2c1=O
InChI Key InChIKey=ICAXEUYZCLRXKY-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 50072822
Affinity DataIC50: 6.20nMAssay Description:Inhibition of [3H]ketanserin binding to rat frontal cortex membrane 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibition of [3H]methylspiperone binding to rat striatal membrane Dopamine receptor D2More data for this Ligand-Target Pair
Affinity DataKi: 1.90nMAssay Description:Binding affinity measured at the 5-hydroxytryptamine 2A receptor by the inhibition of [3H]ketanserin binding to rat cortex using unlabeled mianserin ...More data for this Ligand-Target Pair
Affinity DataKi: 2.40nMAssay Description:Binding affinity measured at the Alpha-1A adrenergic receptor by the inhibition of [3H]prazosin binding to rat cortex using unlabeled WB-4101 for non...More data for this Ligand-Target Pair
Affinity DataKi: 5.40nMAssay Description:Binding affinity measured at the Dopamine receptor D3 by the inhibition of [3H]YM-09151-2 binding to human recombinant CCL 1.3 cells using unlabeled ...More data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Binding affinity measured at the Dopamine receptor D2 by the inhibition of [3H]methylspiperone binding to rat striatum using unlabeled haloperidol fo...More data for this Ligand-Target Pair
Affinity DataKi: 94nMAssay Description:Binding affinity measured at the 5-hydroxytryptamine 1A receptor by the inhibition of [3H]8-OH-DPAT binding to rat cortex using unlabeled buspirone f...More data for this Ligand-Target Pair
Affinity DataKi: 179nMAssay Description:Binding affinity measured at the Dopamine receptor D4 by the inhibition of [3H]spiperone binding to human recombinant CHO cells using unlabeled halop...More data for this Ligand-Target Pair
Affinity DataKi: 239nMAssay Description:Binding affinity measured at the Dopamine receptor D1 by the inhibition of [3H]SCH-23390 binding to rat striatum using unlabeled apomorphine for nons...More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Human)
Centro De InvestigacióN Grupo Ferrer
Curated by ChEMBL
Centro De InvestigacióN Grupo Ferrer
Curated by ChEMBL
Affinity DataKi: 490nMAssay Description:Binding affinity measured at the sigma receptor by the inhibition of [3H]-3-PPP binding to guinea pig cerebellum using unlabeled 3-PPP for nonspecifi...More data for this Ligand-Target Pair