BDBM50072987 2,2,2-Trifluoro-1-(1,2,3,4-tetrahydro-isoquinolin-7-yl)-ethanone::CHEMBL28390

SMILES FC(F)(F)C(=O)c1ccc2CCNCc2c1

InChI Key InChIKey=ZANSSYYYTZWEMO-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50072987   

TargetPhenylethanolamine N-methyltransferase(Bovine)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50072987(2,2,2-Trifluoro-1-(1,2,3,4-tetrahydro-isoquinolin-...)
Affinity DataKi:  5.30E+3nMAssay Description:Inhibitory activity against bovine adrenal phenylethanolamine N-methyl-transferase (PNMT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2018
Entry Details Article
PubMed
TargetPhenylethanolamine N-methyltransferase(Bovine)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50072987(2,2,2-Trifluoro-1-(1,2,3,4-tetrahydro-isoquinolin-...)
Affinity DataKi:  5.70E+3nMAssay Description:In vitro inhibitory activity against bovine adrenal phenylethanolamine N-methyl-transferase (PNMT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
LigandPNGBDBM50072987(2,2,2-Trifluoro-1-(1,2,3,4-tetrahydro-isoquinolin-...)
Affinity DataKi:  1.12E+4nMAssay Description:Inhibition of [3H]clonidine binding to the rat alpha-2-adrenoceptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2018
Entry Details Article
PubMed