BDBM50073188 CHEMBL3408192

SMILES Clc1cncc(-c2ccc(cc2)N2CCOCC2)c1N1CCC2(CCNC2=O)CC1

InChI Key InChIKey=OCKDTDFLJPUWIH-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50073188   

TargetCytochrome P450 3A4(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50073188(CHEMBL3408192)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2016
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50073188(CHEMBL3408192)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2016
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50073188(CHEMBL3408192)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of GST-tagged TNKS2 (873 to 1166 aa) (unknown origin) after 90 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2016
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50073188(CHEMBL3408192)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of GST-tagged TNKS1 (1023 to 1327 aa) (unknown origin) after 90 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2016
Entry Details Article
PubMed