BDBM50073489 1-Ethyl-4-phenyl-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid 2-(4-methoxy-phenyl)-ethyl ester; oxalic acid::CHEMBL1180343::CHEMBL123099

SMILES CCN1CCC(=C(C1)C(=O)OCCc1ccc(OC)cc1)c1ccccc1

InChI Key InChIKey=ZPASGLGRGIEHTG-UHFFFAOYSA-N

Data  5 KI  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 50073489   

TargetMuscarinic acetylcholine receptor M1(Human)
University of Arkansas For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50073489(CHEMBL1180343 | CHEMBL123099 | 1-Ethyl-4-phenyl-1,...)
Affinity DataKi:  170nMAssay Description:Displacement of [3H]NMS from human M1 muscarinic receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
University of Arkansas For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50073489(CHEMBL1180343 | CHEMBL123099 | 1-Ethyl-4-phenyl-1,...)
Affinity DataKi:  420nMAssay Description:Displacement of [3H]NMS from human M5 muscarinic receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
University of Arkansas For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50073489(CHEMBL1180343 | CHEMBL123099 | 1-Ethyl-4-phenyl-1,...)
Affinity DataIC50: 866nMAssay Description:Displacement of [3H]NMS binding to human Muscarinic acetylcholine receptor M5 using membranes from transfected CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
University of Arkansas For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50073489(CHEMBL1180343 | CHEMBL123099 | 1-Ethyl-4-phenyl-1,...)
Affinity DataIC50: 866nMAssay Description:Binding affinity to human M5 muscarinic receptor expressed in cell membranes by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
University of Arkansas For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50073489(CHEMBL1180343 | CHEMBL123099 | 1-Ethyl-4-phenyl-1,...)
Affinity DataKi:  1.10E+3nMAssay Description:Displacement of [3H]NMS from human M2 muscarinic receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
University of Arkansas For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50073489(CHEMBL1180343 | CHEMBL123099 | 1-Ethyl-4-phenyl-1,...)
Affinity DataKi:  1.37E+3nMAssay Description:Displacement of [3H]NMS from human M3 muscarinic receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M4(Human)
University of Arkansas For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50073489(CHEMBL1180343 | CHEMBL123099 | 1-Ethyl-4-phenyl-1,...)
Affinity DataKi:  1.73E+3nMAssay Description:Displacement of [3H]NMS from human M4 muscarinic receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
University of Arkansas For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50073489(CHEMBL1180343 | CHEMBL123099 | 1-Ethyl-4-phenyl-1,...)
Affinity DataIC50: 1.91E+3nMAssay Description:Binding affinity to human M1 muscarinic receptor expressed in cell membranes by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
University of Arkansas For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50073489(CHEMBL1180343 | CHEMBL123099 | 1-Ethyl-4-phenyl-1,...)
Affinity DataIC50: 1.94E+3nMAssay Description:Displacement of [3H]NMS binding to human Muscarinic acetylcholine receptor M1 using membranes from transfected CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
University of Arkansas For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50073489(CHEMBL1180343 | CHEMBL123099 | 1-Ethyl-4-phenyl-1,...)
Affinity DataIC50: 3.85E+4nMAssay Description:Displacement of [3H]NMS binding to human Muscarinic acetylcholine receptor M2 using membranes from transfected CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
University of Arkansas For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50073489(CHEMBL1180343 | CHEMBL123099 | 1-Ethyl-4-phenyl-1,...)
Affinity DataIC50: 3.85E+4nMAssay Description:Binding affinity to human M2 muscarinic receptor expressed in cell membranes by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M4(Human)
University of Arkansas For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50073489(CHEMBL1180343 | CHEMBL123099 | 1-Ethyl-4-phenyl-1,...)
Affinity DataIC50: 4.23E+4nMAssay Description:Binding affinity to human M4 muscarinic receptor expressed in cell membranes by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M4(Human)
University of Arkansas For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50073489(CHEMBL1180343 | CHEMBL123099 | 1-Ethyl-4-phenyl-1,...)
Affinity DataIC50: 4.23E+4nMAssay Description:Displacement of [3H]NMS binding to human Muscarinic acetylcholine receptor M4 using membranes from transfected CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
University of Arkansas For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50073489(CHEMBL1180343 | CHEMBL123099 | 1-Ethyl-4-phenyl-1,...)
Affinity DataIC50: 5.25E+4nMAssay Description:Binding affinity to human M3 muscarinic receptor expressed in cell membranes by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
University of Arkansas For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50073489(CHEMBL1180343 | CHEMBL123099 | 1-Ethyl-4-phenyl-1,...)
Affinity DataIC50: 5.25E+4nMAssay Description:Displacement of [3H]-NMS binding to human Muscarinic acetylcholine receptor M3 using membranes from transfected CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2012
Entry Details Article
PubMed