BDBM50073606 CHEMBL1958265

SMILES Oc1ccc(cc1O)-c1csc(N\N=C2/C(=O)Nc3ccccc23)n1

InChI Key InChIKey=IGNJYQFJDSQAGT-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50073606   

TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50073606(CHEMBL1958265)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of HIV1 reverse transcriptase-associated DNA polymerase-independent RNase H activity after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50073606(CHEMBL1958265)
Affinity DataIC50: 900nMAssay Description:Inhibition of HIV1 reverse transcriptase-associated RNA-dependent DNA polymerase activity after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50073606(CHEMBL1958265)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of RNA-dependent DNA polymerase activity of wild type Human immunodeficiency virus 1 reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
Magna Graecia University of Catanzaro

Curated by ChEMBL
LigandPNGBDBM50073606(CHEMBL1958265)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of ribonuclease H activity of Human immunodeficiency virus 1 reverse transcriptase Lys103Asn mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
Magna Graecia University of Catanzaro

Curated by ChEMBL
LigandPNGBDBM50073606(CHEMBL1958265)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of RNA-dependent DNA polymerase activity of Human immunodeficiency virus 1 reverse transcriptase Lys103Asn mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50073606(CHEMBL1958265)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of RNA-dependent DNA polymerase activity of Human immunodeficiency virus 1 reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50073606(CHEMBL1958265)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of ribonuclease H activity of wild type Human immunodeficiency virus 1 reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50073606(CHEMBL1958265)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of ribonuclease H activity of HIV1 reverse transcriptase using as poly(dC)-[3H]poly(rG) as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Armed Police Forces Hospital of Sichuan

Curated by ChEMBL
LigandPNGBDBM50073606(CHEMBL1958265)
Affinity DataIC50: 2.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed