BDBM50073694 (R)-7-Isopropyl-5-methyl-2-(4-methyl-pentyl)-7,8-dihydro-3H,5H-imidazo[2,1-b]purin-4-one::CHEMBL18524

SMILES CC(C)CCCc1nc2N3C[C@H](N=C3N(C)C(=O)c2[nH]1)C(C)C

InChI Key InChIKey=KKECCKBNNBKYMQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50073694   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bovine)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50073694((R)-7-Isopropyl-5-methyl-2-(4-methyl-pentyl)-7,8-d...)
Affinity DataIC50: 6nMAssay Description:Inhibition of c-GMP specific phosphodiesterase PDE5 of bovine lungMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50073694((R)-7-Isopropyl-5-methyl-2-(4-methyl-pentyl)-7,8-d...)
Affinity DataIC50: 12nMAssay Description:Optimum inhibitory concentration required to inhibit c-GMP specific phosphodiesterase 1 (PDE1) of bovine aortaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50073694((R)-7-Isopropyl-5-methyl-2-(4-methyl-pentyl)-7,8-d...)
Affinity DataIC50: 6.50E+4nMAssay Description:Optimum inhibitory concentration required to inhibit cGMP specific phosphodiesterase 3 (PDE3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed