BDBM50073773 CHEMBL439841::CHEMBL537838::N*2*-(2-Amino-ethyl)-9-ethyl-N*6*-(3-fluoro-phenyl)-9H-purine-2,6-diamine; hydrochloride

SMILES CCn1cnc2c(Nc3cccc(F)c3)nc(NCCN)nc12

InChI Key InChIKey=WADPIXLSLDNKJV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50073773   

TargetCyclin-dependent kinase 1(Human)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073773(CHEMBL439841 | N*2*-(2-Amino-ethyl)-9-ethyl-N*6*-(...)
Affinity DataIC50: 600nMAssay Description:Inhibition of Cyclin-dependent kinase 1, CDK1-related human bladder carcinoma (T24) cell proliferationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073773(CHEMBL439841 | N*2*-(2-Amino-ethyl)-9-ethyl-N*6*-(...)
Affinity DataIC50: 600nMAssay Description:Inhibitory activity against cyclin-dependent kinase 1 (CDK1) was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed