BDBM50073789 CHEMBL174162::N*2*-(4-Amino-cyclohexyl)-9-ethyl-N*6*-(3-trifluoromethyl-phenyl)-9H-purine-2,6-diamine

SMILES CCn1cnc2c(Nc3cccc(c3)C(F)(F)F)nc(N[C@@H]3CC[C@H](N)CC3)nc12

InChI Key InChIKey=ITNUIFJLBYTNFE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50073789   

TargetCyclin-dependent kinase 1(Human)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073789(N*2*-(4-Amino-cyclohexyl)-9-ethyl-N*6*-(3-trifluor...)
Affinity DataIC50: 290nMAssay Description:Inhibition of Cyclin-dependent kinase 1, CDK1-related human bladder carcinoma (T24) cell proliferationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed