BDBM50074238 6-Ethyl-5-ethylsulfanylcarbonyl-2-phenyl-4-propyl-nicotinic acid 2,2,3,3,3-pentafluoro-propyl ester::CHEMBL164200

SMILES CCCc1c(C(=O)SCC)c(CC)nc(-c2ccccc2)c1C(=O)OCC(F)(F)C(F)(F)F

InChI Key InChIKey=CFXTXARKEUSPHR-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50074238   

TargetAdenosine receptor A3(Human)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50074238(6-Ethyl-5-ethylsulfanylcarbonyl-2-phenyl-4-propyl-...)
Affinity DataKi:  446nMAssay Description:Displacement of specific [125 I]AB-MECA binding at human Adenosine A3 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50074238(6-Ethyl-5-ethylsulfanylcarbonyl-2-phenyl-4-propyl-...)
Affinity DataKi:  5.68E+3nMAssay Description:Displacement of specific [3H]-CGS- 21680R-PIA binding to Adenosine A1 receptor in rat brain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50074238(6-Ethyl-5-ethylsulfanylcarbonyl-2-phenyl-4-propyl-...)
Affinity DataKi:  1.40E+4nMAssay Description:Inhibition of [3H]-CGS- 21680 binding to Adenosine A2A receptor in rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed