BDBM50074364 CHEMBL350356::N*2*-(2-Bromo-4-isopropyl-phenyl)-N*4*-butyl-N*2*,N*4*-diethyl-6-methyl-pyrimidine-2,4-diamine

SMILES CCCCN(CC)c1cc(C)nc(n1)N(CC)c1ccc(cc1Br)C(C)C

InChI Key InChIKey=CGXREZRUTGTAGJ-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50074364   

TargetCorticotropin-releasing factor receptor 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50074364(N*2*-(2-Bromo-4-isopropyl-phenyl)-N*4*-butyl-N*2*,...)
Affinity DataKi:  18nMAssay Description:Inhibition of [125I]ovine-CRF binding to corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50074364(N*2*-(2-Bromo-4-isopropyl-phenyl)-N*4*-butyl-N*2*,...)
Affinity DataKi:  19nMAssay Description:Binding affinity for human recombinant corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed