BDBM50074832 CHEMBL156605

SMILES O=C(CN1c2ccccc2N(c2ccccc2)C(=O)C(NC(=O)Nc2ccccc2)C1=O)Nc1ccccc1

InChI Key InChIKey=PDWDMFQEOPBNJU-UHFFFAOYSA-N

Data  17 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 21 hits for monomerid = 50074832   

TargetCholecystokinin receptor type A(Human)
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50074832(CHEMBL156605)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [125I]CCK from CCK1R TM3 (unknown origin) containing T3.28V, T3.29S chimeric mutant expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Human)
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50074832(CHEMBL156605)
Affinity DataEC50: >1.00E+3nMAssay Description:Activity at CCK1R (unknown origin) expressed in CHO cells assessed as stimulation of intracellular calcium responsesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Human)
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50074832(CHEMBL156605)
Affinity DataIC50: 12nMAssay Description:Displacement of [125I]CCK from CCK2R TM7 (unknown origin) containing L7.39H chimeric mutant expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Human)
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50074832(CHEMBL156605)
Affinity DataIC50: 68nMAssay Description:Displacement of [125I]CCK from CCK2R TM6 (unknown origin) containing 16.51V, F6.52Y chimeric mutant expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Human)
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50074832(CHEMBL156605)
Affinity DataIC50: 51nMAssay Description:Displacement of [125I]CCK from CCK2R TM3 (unknown origin) containing T3.28V, T3.29S chimeric mutant expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Human)
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50074832(CHEMBL156605)
Affinity DataIC50: 188nMAssay Description:Displacement of [125I]CCK from CCK2R TM2 (unknown origin) containing N2.61T chimeric mutant expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Human)
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50074832(CHEMBL156605)
Affinity DataIC50: 6.30nMAssay Description:Displacement of [125I]BDZ2 from CCK2R TM7 (unknown origin) containing L7.39H chimeric mutant expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Human)
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50074832(CHEMBL156605)
Affinity DataIC50: 33nMAssay Description:Displacement of [125I]BDZ2 from CCK2R TM6 (unknown origin) containing 16.51V, F6.52Y chimeric mutant expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Human)
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50074832(CHEMBL156605)
Affinity DataIC50: 135nMAssay Description:Displacement of [125I]BDZ2 from CCK2R TM3 (unknown origin) containing T3.28V, T3.29S chimeric mutant expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Human)
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50074832(CHEMBL156605)
Affinity DataIC50: 303nMAssay Description:Displacement of [125I]CCK from CCK1R TM7 (unknown origin) containing L7.39H chimeric mutant expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Human)
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50074832(CHEMBL156605)
Affinity DataIC50: 317nMAssay Description:Displacement of [125I]CCK from CCK1R TM6 (unknown origin) containing 16.51V, F6.52Y chimeric mutant expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50074832(CHEMBL156605)
Affinity DataIC50: 32nMAssay Description:Displacement of [125I]BDZ1 from CCK2R (unknown origin) expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Human)
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50074832(CHEMBL156605)
Affinity DataIC50: 128nMAssay Description:Displacement of [125I]CCK from CCK1R TM2 (unknown origin) containing N2.61T chimeric mutant expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Human)
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50074832(CHEMBL156605)
Affinity DataIC50: 505nMAssay Description:Displacement of [125I]BDZ1 from CCK1R TM7 (unknown origin) containing L7.39H chimeric mutant expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Human)
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50074832(CHEMBL156605)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [125I]BDZ1 from CCK1R TM6 (unknown origin) containing 16.51V, F6.52Y chimeric mutant expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Human)
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50074832(CHEMBL156605)
Affinity DataIC50: 259nMAssay Description:Displacement of [125I]BDZ1 from CCK1R TM3 (unknown origin) containing T3.28V, T3.29S chimeric mutant expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Human)
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50074832(CHEMBL156605)
Affinity DataEC50:  0.0390nMAssay Description:Activity at CCK1R (unknown origin) expressed in CHO cells assessed as CCK EC50 measured as intracellular calcium responses at 1000 nM (Rvb = 7 to 14 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Human)
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50074832(CHEMBL156605)
Affinity DataEC50:  0.0140nMAssay Description:Activity at CCK1R (unknown origin) expressed in CHO cells assessed as CCK EC50 measured as intracellular calcium responses at 100 nM (Rvb = 7 to 14 p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Human)
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50074832(CHEMBL156605)
Affinity DataEC50:  0.0190nMAssay Description:Activity at CCK1R (unknown origin) expressed in CHO cells assessed as CCK EC50 measured as intracellular calcium responses at 10 nM (Rvb = 7 to 14 pM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Human)
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50074832(CHEMBL156605)
Affinity DataIC50: 541nMAssay Description:Displacement of [125I]CCK from CCK1R (unknown origin) expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50074832(CHEMBL156605)
Affinity DataIC50: 450nMAssay Description:Displacement of [125I]CCK from CCK2R (unknown origin) expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMed