BDBM50075063 ((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R,3S,4R,5R)-3,4-dihydroxy-5-[4-(4-methoxy-phenyl)-thiazol-2-yl]-tetrahydro-furan-2-ylmethyl ester::CHEMBL333001

SMILES CCC(C)[C@H](N)C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)c1nc(cs1)-c1ccc(OC)cc1

InChI Key InChIKey=WNORCWSRNMBRBU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50075063   

TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50075063(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)
Affinity DataIC50: 100nMAssay Description:Compound tested for the inhibition of Staphylococcus aureus isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIsoleucine--tRNA ligase, cytoplasmic(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50075063(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)
Affinity DataIC50: 100nMAssay Description:Inhibition of Escherichia coli isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIsoleucine--tRNA ligase, cytoplasmic(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50075063(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)
Affinity DataIC50: 200nMAssay Description:Compound tested for the inhibition of human isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed