BDBM50075302 (3-ethynylphenyl)(difluoro)methylphosphonate::CHEMBL151248::[(3-Ethynyl-phenyl)-difluoro-methyl]-phosphonic acid

SMILES OP(O)(=O)C(F)(F)c1cccc(c1)C#C

InChI Key InChIKey=JOQLGVYSGPNPLV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50075302   

TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Tokyo University of Pharmacy & Life Science

Curated by ChEMBL
LigandPNGBDBM50075302([(3-Ethynyl-phenyl)-difluoro-methyl]-phosphonic ac...)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibitory potency for the protein tyrosine phosphatase (PTP 1B)-catalyzed hydrolysis of p-nitrophenol phosphateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Tokyo University of Pharmacy & Life Science

Curated by ChEMBL
LigandPNGBDBM50075302([(3-Ethynyl-phenyl)-difluoro-methyl]-phosphonic ac...)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibitory concentration against protein-tyrosine phosphatase 1B (PTB 1B)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed