BDBM50075690 3-[4-(2-Hydroxy-ethyl)-piperazine-1-carbonyl]-6,7-dimethoxy-1-[(E)-2-(3,4,5-trimethoxy-phenyl)-vinyl]-naphthalene-2-carboxylic acid methyl ester::CHEMBL26556

SMILES COC(=O)c1c(cc2cc(OC)c(OC)cc2c1\C=C\c1cc(OC)c(OC)c(OC)c1)C(=O)N1CCN(CCO)CC1

InChI Key InChIKey=DUJJMBYYIUKDMO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50075690   

LigandPNGBDBM50075690(3-[4-(2-Hydroxy-ethyl)-piperazine-1-carbonyl]-6,7-...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibitory activity against phosphodiesterase 1 (PDE I), isolated from cardiac ventricleMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Human)
Tanabe Seiyaku

Curated by ChEMBL
LigandPNGBDBM50075690(3-[4-(2-Hydroxy-ethyl)-piperazine-1-carbonyl]-6,7-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against phosphodiesterase 3 (PDE 3) isolated from cardiac ventricleMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Dog)
Tanabe Seiyaku

Curated by ChEMBL
LigandPNGBDBM50075690(3-[4-(2-Hydroxy-ethyl)-piperazine-1-carbonyl]-6,7-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against phosphodiesterase 5 (PDE V), isolated from cardiac ventricleMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed