BDBM50075698 1-(3-Bromo-4,5-dimethoxy-phenyl)-6-ethoxy-3-[4-(2-hydroxy-ethyl)-piperazine-1-carbonyl]-7-methoxy-naphthalene-2-carboxylic acid methyl ester::CHEMBL24495

SMILES CCOc1cc2cc(C(=O)N3CCN(CCO)CC3)c(C(=O)OC)c(-c3cc(Br)c(OC)c(OC)c3)c2cc1OC

InChI Key InChIKey=CBNVDUFLBYGPJT-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50075698   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Dog)
Tanabe Seiyaku

Curated by ChEMBL
LigandPNGBDBM50075698(1-(3-Bromo-4,5-dimethoxy-phenyl)-6-ethoxy-3-[4-(2-...)
Affinity DataIC50: 17nMAssay Description:Inhibitory activity against phosphodiesterase 5 (PDE V), isolated from cardiac ventricleMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50075698(1-(3-Bromo-4,5-dimethoxy-phenyl)-6-ethoxy-3-[4-(2-...)
Affinity DataIC50: 6.10E+4nMAssay Description:Inhibitory activity against phosphodiesterase 1 (PDE I), isolated from cardiac ventricleMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50075698(1-(3-Bromo-4,5-dimethoxy-phenyl)-6-ethoxy-3-[4-(2-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of canine lung Phosphodiesterase 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Human)
Tanabe Seiyaku

Curated by ChEMBL
LigandPNGBDBM50075698(1-(3-Bromo-4,5-dimethoxy-phenyl)-6-ethoxy-3-[4-(2-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against phosphodiesterase 3 (PDE 3) isolated from cardiac ventricleMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Tanabe Seiyaku

Curated by ChEMBL
LigandPNGBDBM50075698(1-(3-Bromo-4,5-dimethoxy-phenyl)-6-ethoxy-3-[4-(2-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of canine adrenal gland Phosphodiesterase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed