BDBM50075739 CHEMBL3415588

SMILES COC[C@H](N)CNc1cnc(C(N)=O)c(Nc2cc(C)cc(C)n2)c1

InChI Key InChIKey=AQIMRZVVRRUVKP-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50075739   

TargetTyrosine-protein kinase SYK(Human)
Merck

Curated by ChEMBL

LigandBDBM50075739(CHEMBL3415588)Copy SMILESCopy InChI

Affinity DataIC50: 0.800nMAssay Description:Inhibition of full-length GST-tagged human Syk preincubated for 10 mins followed by peptide substrate/ATP addition measured after 45 mins by TR-FRET ...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
4/24/2016
Entry Details Article
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TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck

Curated by ChEMBL

LigandBDBM50075739(CHEMBL3415588)Copy SMILESCopy InChI

Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of ERG channel expressed in human embryonic kidney cells assessed as tail current amplitude measured for 3 to 30 mins by PatchXpress elect...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
4/24/2016
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL