BDBM50075747 CHEMBL3415597

SMILES Cc1nc(Nc2cc(N[C@@H]3CCCC[C@@H]3N)cnc2C(N)=O)cc(OCC(C)(C)O)n1

InChI Key InChIKey=GKCOFLVDCMKDGE-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50075747   

TargetTyrosine-protein kinase SYK(Human)
Merck

Curated by ChEMBL

LigandBDBM50075747(CHEMBL3415597)Copy SMILESCopy InChI

Affinity DataIC50: 0.200nMAssay Description:Inhibition of full-length GST-tagged human Syk preincubated for 10 mins followed by peptide substrate/ATP addition measured after 45 mins by TR-FRET ...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
4/24/2016
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck

Curated by ChEMBL

LigandBDBM50075747(CHEMBL3415597)Copy SMILESCopy InChI

Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of ERG channel expressed in human embryonic kidney cells assessed as tail current amplitude measured for 3 to 30 mins by PatchXpress elect...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
4/24/2016
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL