BDBM50076876 CHEMBL417266::[4-(4-Fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-thiazol-2-yl]-acetonitrile

SMILES CS(=O)(=O)c1ccc(cc1)-c1sc(CC#N)nc1-c1ccc(F)cc1

InChI Key InChIKey=WYEGNTCQPRBFDR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50076876   

TargetProstaglandin G/H synthase 2(Human)
G.D. Searle-Monsanto

Curated by ChEMBL
LigandPNGBDBM50076876([4-(4-Fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-...)
Affinity DataIC50: 350nMAssay Description:Inhibition of human cyclooxygenase-2 (hCOX-2) enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
G.D. Searle-Monsanto

Curated by ChEMBL
LigandPNGBDBM50076876([4-(4-Fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human cyclooxygenase-1 (hCOX-1) enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed