BDBM50077083 4-[(4-Benzo[1,3]dioxol-5-ylmethyl-piperazin-1-yl)-phenyl-methyl]-N,N-diethyl-benzamide::CHEMBL27161

SMILES CCN(CC)C(=O)c1ccc(cc1)C(N1CCN(Cc2ccc3OCOc3c2)CC1)c1ccccc1

InChI Key InChIKey=GOLMFFFPKWMDPL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50077083   

TargetDelta-type opioid receptor(Human)
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50077083(4-[(4-Benzo[1,3]dioxol-5-ylmethyl-piperazin-1-yl)-...)
Affinity DataIC50: 1.40nMAssay Description:Compound was tested for inhibition of binding of [3H]- -naltrindole (0.15 nM) to membranes from CHO cells expressing human delta opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50077083(4-[(4-Benzo[1,3]dioxol-5-ylmethyl-piperazin-1-yl)-...)
Affinity DataIC50: 3.90E+3nMAssay Description:Binding affinity towards Opioid receptor kappa 1 using [3H]- U-69,593 (1.5 nM) as radioligand in guinea pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50077083(4-[(4-Benzo[1,3]dioxol-5-ylmethyl-piperazin-1-yl)-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity towards mu opioid receptor using [3H]- -DAMGO (1.5 nM) as radioligand in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed