BDBM50077085 CHEMBL27432::N,N-Diethyl-4-{phenyl-[4-(1,2,3,4-tetrahydro-naphthalen-2-ylmethyl)-piperazin-1-yl]-methyl}-benzamide

SMILES CCN(CC)C(=O)c1ccc(cc1)C(N1CCN(CC2CCc3ccccc3C2)CC1)c1ccccc1

InChI Key InChIKey=QXAWSSWYWHHUAE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50077085   

TargetDelta-type opioid receptor(Human)
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50077085(N,N-Diethyl-4-{phenyl-[4-(1,2,3,4-tetrahydro-napht...)
Affinity DataIC50: 1.80nMAssay Description:Compound was tested for inhibition of binding of [3H]- -naltrindole (0.15 nM) to membranes from CHO cells expressing human delta opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50077085(N,N-Diethyl-4-{phenyl-[4-(1,2,3,4-tetrahydro-napht...)
Affinity DataIC50: 6.24E+3nMAssay Description:Binding affinity towards mu opioid receptor using [3H]- -DAMGO (1.5 nM) as radioligand in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed