BDBM50077257 (4-Isopropyl-phenyl)-carbamic acid (S)-3a-methyl-1,2,3,3a,8,8a-hexahydro-pyrrolo[2,3-b]indol-5-yl ester::CHEMBL54470

SMILES CC(C)c1ccc(NC(=O)Oc2ccc3NC4NCC[C@@]4(C)c3c2)cc1

InChI Key InChIKey=ZIGIADNCAWZUAB-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50077257   

TargetCholinesterase(Human)
National Institute On Aging Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50077257((4-Isopropyl-phenyl)-carbamic acid (S)-3a-methyl-1...)
Affinity DataIC50: 1nMAssay Description:Ability to inhibit butyrylcholinesterase (BChE), freshly prepared from human plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholinesterase(Human)
National Institute On Aging Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50077257((4-Isopropyl-phenyl)-carbamic acid (S)-3a-methyl-1...)
Affinity DataIC50: 1nMAssay Description:Inhibition of human plasma BChE using s-butyrylthiocholine as substrate preincubated for 30 mins followed by substrate addition and measured after 25...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Julius Maximilian University W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50077257((4-Isopropyl-phenyl)-carbamic acid (S)-3a-methyl-1...)
Affinity DataIC50: 110nMAssay Description:Inhibition of human erythrocyte AChE using acetyl-(beta-methyl)thiocholine as substrate preincubated for 30 mins followed by substrate addition and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Julius Maximilian University W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50077257((4-Isopropyl-phenyl)-carbamic acid (S)-3a-methyl-1...)
Affinity DataIC50: 110nMAssay Description:Ability to inhibit acetylcholinesterase (AChE), freshly prepared from human erythrocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed