BDBM50077370 CHEMBL301675::Carbonic acid ethyl ester (R)-3-hydroxycarbamoyl-2-(4-methoxy-benzenesulfonyl)-1,2,3,4-tetrahydro-isoquinolin-7-yl ester

SMILES CCOC(=O)Oc1ccc2C[C@@H](N(Cc2c1)S(=O)(=O)c1ccc(OC)cc1)C(=O)NO

InChI Key InChIKey=VZEDRBAGPXKVHL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50077370   

TargetNeutrophil collagenase(Human)
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50077370(Carbonic acid ethyl ester (R)-3-hydroxycarbamoyl-2...)
Affinity DataIC50: 2nMAssay Description:Inhibition of human neutrophil collagenase [Matrix Metalloprotease-8, MMP-8]More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed