BDBM50077641 (6aR,12bS)-2-Methyl-5,6,6a,7,8,12b-hexahydro-4,6-diaza-benzo[c]phenanthrene-10,11-diol::CHEMBL275379

SMILES Cc1cnc2CN[C@@H]3CCc4cc(O)c(O)cc4[C@H]3c2c1

InChI Key InChIKey=OTRPXYDXEWMYIL-UHFFFAOYSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50077641   

TargetD(1A) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50077641((6aR,12bS)-2-Methyl-5,6,6a,7,8,12b-hexahydro-4,6-d...)
Affinity DataEC50:  110nMAssay Description:Potency in adenylate cyclase functional assay against Dopamine receptor D1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50077641((6aR,12bS)-2-Methyl-5,6,6a,7,8,12b-hexahydro-4,6-d...)
Affinity DataKi:  240nMAssay Description:Binding affinity to Dopamine receptor D1 by using radioligand [125I]SCH-23982 in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50077641((6aR,12bS)-2-Methyl-5,6,6a,7,8,12b-hexahydro-4,6-d...)
Affinity DataKi:  1.20E+4nMAssay Description:Binding affinity to human Dopamine receptor D2 by using radioligand [3H]spiperone in LTK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed