BDBM50077689 (3R,4R)-4-[4-(3-Benzyloxy-propoxy)-phenyl]-3-(naphthalen-2-ylmethoxy)-piperidine::(3R,4R)-4-{4-[3-(BENZYLOXY)PROPOXY]PHENYL}-3-(2-NAPHTHYLMETHOXY)PIPERIDINE::CHEMBL31466

SMILES c1ccc(cc1)COCCCOc2ccc(cc2)[C@H]3CCNC[C@@H]3OCc4ccc5ccccc5c4

InChI Key InChIKey=SBQHXMHGXWOGFR-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50077689   

TargetRenin(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50077689((3R,4R)-4-{4-[3-(BENZYLOXY)PROPOXY]PHENYL}-3-(2-NA...)
Affinity DataIC50: 5nMAssay Description:Inhibitory activity against purified recombinant human reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50077689((3R,4R)-4-{4-[3-(BENZYLOXY)PROPOXY]PHENYL}-3-(2-NA...)
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant renin in bufferMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetRenin(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50077689((3R,4R)-4-{4-[3-(BENZYLOXY)PROPOXY]PHENYL}-3-(2-NA...)
Affinity DataIC50: 8nMAssay Description:In vitro inhibitory activity against purified recombinant human reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50077689((3R,4R)-4-{4-[3-(BENZYLOXY)PROPOXY]PHENYL}-3-(2-NA...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of renin in plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetRenin(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50077689((3R,4R)-4-{4-[3-(BENZYLOXY)PROPOXY]PHENYL}-3-(2-NA...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibitory activity against human plasma reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed