BDBM50077791 (2S,3R,6S)-2-Hydroxycarbamoyl-6-methylcarbamoyl-4-oxo-3-(3-phenyl-propyl)-1-oxa-5,10-diaza-cyclotetradecane-10-carboxylic acid tert-butyl ester::CHEMBL32631

SMILES CNC(=O)[C@@H]1CCCN(CCCCO[C@@H]([C@@H](CCCc2ccccc2)C(=O)N1)C(=O)NO)C(=O)OC(C)(C)C

InChI Key InChIKey=PYHVMKLBOIYJOG-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50077791   

TargetNeutrophil collagenase(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50077791((2S,3R,6S)-2-Hydroxycarbamoyl-6-methylcarbamoyl-4-...)
Affinity DataKi:  13nMAssay Description:Inhibition of Matrix metalloprotease-8 (MMP-8)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50077791((2S,3R,6S)-2-Hydroxycarbamoyl-6-methylcarbamoyl-4-...)
Affinity DataKi:  19nMAssay Description:Inhibition of Matrix metalloprotease-9 (MMP-9)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50077791((2S,3R,6S)-2-Hydroxycarbamoyl-6-methylcarbamoyl-4-...)
Affinity DataKi:  373nMAssay Description:Inhibition of Matrix metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50077791((2S,3R,6S)-2-Hydroxycarbamoyl-6-methylcarbamoyl-4-...)
Affinity DataKi:  1.07E+3nMAssay Description:Inhibition of Matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed