BDBM50077953 4-(1-methyl-2-(piperidin-4-yl)-4-(3-(trifluoromethyl)phenyl)-1H-imidazol-5-yl)-N-((R)-1-phenylethyl)pyrimidin-2-amine::CHEMBL307435::{4-[3-Methyl-2-piperidin-4-yl-5-(3-trifluoromethyl-phenyl)-3H-imidazol-4-yl]-pyrimidin-2-yl}-((R)-1-phenyl-ethyl)-amine

SMILES C[C@@H](Nc1nccc(n1)-c1c(nc(C2CCNCC2)n1C)-c1cccc(c1)C(F)(F)F)c1ccccc1

InChI Key InChIKey=QICPQLFMWYQJGX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50077953   

TargetMitogen-activated protein kinase 9(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50077953({4-[3-Methyl-2-piperidin-4-yl-5-(3-trifluoromethyl...)
Affinity DataIC50: 300nMAssay Description:Inhibition of c-Jun N-terminal kinase 2-alpha 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50077953({4-[3-Methyl-2-piperidin-4-yl-5-(3-trifluoromethyl...)
Affinity DataIC50: 675nMAssay Description:Inhibition of JNK2alpha1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Eberhard Karls University Tuebingen

Curated by ChEMBL
LigandPNGBDBM50077953({4-[3-Methyl-2-piperidin-4-yl-5-(3-trifluoromethyl...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human c-RAF at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed