BDBM50078351 CHEMBL3414703

SMILES COC[C@H]1CSC(N)=N[C@]1(C)c1ccc(F)cc1F

InChI Key InChIKey=WRFZKUFJPBAFHG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50078351   

TargetBeta-secretase 1(Human)
Eurofarma Laboratorios

Curated by ChEMBL
LigandPNGBDBM50078351(CHEMBL3414703)
Affinity DataIC50: 850nMAssay Description:Inhibition of BACE1 in human H4 cells overexpressing APP695 assessed as sAPPbeta level after 18 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2016
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Eurofarma Laboratorios

Curated by ChEMBL
LigandPNGBDBM50078351(CHEMBL3414703)
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of BACE1 (unknown origin) using biotin-GLTNIKTEEISEISYEVEFR-C[Oregon Green]KK-OH as substrate after 3 hrs by fluorescence polarization ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2016
Entry Details Article
PubMed
TargetCathepsin D(Human)
Eurofarma Laboratorios

Curated by ChEMBL
LigandPNGBDBM50078351(CHEMBL3414703)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CatD (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2016
Entry Details Article
PubMed