BDBM50078466 6-[(3-Methoxy-phenylamino)-methyl]-5-methyl-pyrido[2,3-d]pyrimidine-2,4-diamine::CHEMBL80070

SMILES COc1cccc(NCc2cnc3nc(N)nc(N)c3c2C)c1

InChI Key InChIKey=SZCIRFNJPTVWPC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50078466   

TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50078466(6-[(3-Methoxy-phenylamino)-methyl]-5-methyl-pyrido...)
Affinity DataIC50: 68.9nMAssay Description:Inhibition of dihydrofolate reductase (DHFR) from Pneumocystis carinii(pc)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50078466(6-[(3-Methoxy-phenylamino)-methyl]-5-methyl-pyrido...)
Affinity DataIC50: 7.40nMAssay Description:Inhibition of dihydrofolate reductase (DHFR) from Toxoplasma gondii(tg)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50078466(6-[(3-Methoxy-phenylamino)-methyl]-5-methyl-pyrido...)
Affinity DataIC50: 80.1nMAssay Description:Inhibition of dihydrofolate reductase (DHFR) from rat liver (rl)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed