BDBM50078472 5-Methyl-6-phenylaminomethyl-pyrido[2,3-d]pyrimidine-2,4-diamine::CHEMBL79123

SMILES Cc1c(CNc2ccccc2)cnc2nc(N)nc(N)c12

InChI Key InChIKey=HXPWAEYYJWNMHC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50078472   

TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50078472(5-Methyl-6-phenylaminomethyl-pyrido[2,3-d]pyrimidi...)
Affinity DataIC50: 17nMAssay Description:Inhibition of dihydrofolate reductase (DHFR) from Toxoplasma gondii(tg)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50078472(5-Methyl-6-phenylaminomethyl-pyrido[2,3-d]pyrimidi...)
Affinity DataIC50: 170nMAssay Description:Inhibition of dihydrofolate reductase (DHFR) from rat liver (rl)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50078472(5-Methyl-6-phenylaminomethyl-pyrido[2,3-d]pyrimidi...)
Affinity DataIC50: 80nMAssay Description:Inhibition of dihydrofolate reductase (DHFR) from Pneumocystis carinii(pc)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed