BDBM50078498 4-[3-(4-Benzyl-piperidin-1-yl)-prop-1-ynyl]-phenol::CHEMBL79904

SMILES Oc1ccc(cc1)C#CCN1CCC(Cc2ccccc2)CC1

InChI Key InChIKey=YZFVGINTZAFMNW-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50078498   

LigandPNGBDBM50078498(4-[3-(4-Benzyl-piperidin-1-yl)-prop-1-ynyl]-phenol...)
Affinity DataIC50: 1.00E+5nMAssay Description:Antagonistic activity against rat NR1A/2A receptor, expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50078498(4-[3-(4-Benzyl-piperidin-1-yl)-prop-1-ynyl]-phenol...)
Affinity DataIC50: 1.00E+5nMAssay Description:The compound was tested for antagonistic activity against rat NR1A/2C receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Cocensys

Curated by ChEMBL
LigandPNGBDBM50078498(4-[3-(4-Benzyl-piperidin-1-yl)-prop-1-ynyl]-phenol...)
Affinity DataIC50: 1.70E+3nMAssay Description:Binding affinity against Dopamine receptor D2 from rat using [3H]raclopride as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50078498(4-[3-(4-Benzyl-piperidin-1-yl)-prop-1-ynyl]-phenol...)
Affinity DataIC50: 100nMAssay Description:Antagonistic activity against rat NR1A/2B receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rat)
Cocensys

Curated by ChEMBL
LigandPNGBDBM50078498(4-[3-(4-Benzyl-piperidin-1-yl)-prop-1-ynyl]-phenol...)
Affinity DataIC50: 100nMAssay Description:Concentration required for 50% Inhibition of responses at cloned NR1A/2AB N-methyl-D-aspartate (NMDA) expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rat)
Cocensys

Curated by ChEMBL
LigandPNGBDBM50078498(4-[3-(4-Benzyl-piperidin-1-yl)-prop-1-ynyl]-phenol...)
Affinity DataIC50: 1.00E+5nMAssay Description:Concentration required for 50% Inhibition of responses at cloned NR1A/2C N-methyl-D-aspartate (NMDA) expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rat)
Cocensys

Curated by ChEMBL
LigandPNGBDBM50078498(4-[3-(4-Benzyl-piperidin-1-yl)-prop-1-ynyl]-phenol...)
Affinity DataIC50: 1.00E+5nMAssay Description:Concentration required for 50% Inhibition of responses at cloned NR1A/2A N-methyl-D-aspartate (NMDA) expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University Munster

Curated by ChEMBL
LigandPNGBDBM50078498(4-[3-(4-Benzyl-piperidin-1-yl)-prop-1-ynyl]-phenol...)
Affinity DataIC50: 100nMAssay Description:Antagonist activity at GluN1A/GluN2B receptor (unknown origin) expressed in Xenopus oocytes by voltage clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed