BDBM50078548 3-[(3R,3aS,8aS)-3-(4-Carbamimidoyl-butyl)-2-oxo-1-(5-phenyl-pentyl)-1,2,3,3a,8,8a-hexahydro-indeno[2,1-b]pyrrol-6-yl]-N,N-diethyl-benzamide::CHEMBL44891

SMILES CCN(CC)C(=O)c1cccc(c1)-c1ccc2[C@H]3[C@H](Cc2c1)N(CCCCCc1ccccc1)C(=O)[C@@H]3CCCCC(N)=N

InChI Key InChIKey=ZIDHHXAACGJDRP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50078548   

TargetProthrombin(Human)
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50078548(3-[(3R,3aS,8aS)-3-(4-Carbamimidoyl-butyl)-2-oxo-1-...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50078548(3-[(3R,3aS,8aS)-3-(4-Carbamimidoyl-butyl)-2-oxo-1-...)
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50078548(3-[(3R,3aS,8aS)-3-(4-Carbamimidoyl-butyl)-2-oxo-1-...)
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of activated Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed